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Antimicrobial Drugs

pharmacology mcqs questions

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Which of the following sulphonamides is available as an oral ...

Subject :-


Correct answer :- *** Hidden ***

Explanation :-

pidly absorbed rapidly excreted. It is 50% plasma protein bound 20-40% acetylated. It has good penetration in CSF brain, therefore used in the treatment of meningitis.

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2013-07-01 13:57:22
following sulphonamides available oral preparation SulphacetamideSulphadiazine Silver sulphadiazineMafenide Sulfadiazine issulfonamide can used orally itrapidly absorbed rapidly excreted It50% plasma protein bound 20-40% acetylated has good penetrationCSF brain therefore used intreatmentmeningitis Ref: EssentialsMedical Pharmacology 5th Edition Pages 641-3
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Subject :-pharmacology

Topic :- Antimicrobial Drugs

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Subject :-pharmacology

Topic :- Antimicrobial Drugs

following represent mechanism action tetracycline Inhibits peptidyl transferaseCauses misreading mRNACauses termination peptide chain elongationBinds site and inhibits attachment tRNA Tetracyclines bacteriostatic antibiotics inhibits protein synthesis binding 30S ribosomal subunit and prevents attachment aminoacyl tRNA mRNA ribosome complex result peptide chain fails grow Ref: Essentials Medical Pharmacology 5th Edition Page 668-73 .......

Which drug does not need dose adjustment patient with creatinine clearance

Subject :-pharmacology

Topic :- Antimicrobial Drugs

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Antipseudomonal action characteristic which the following antimicrobials?

Subject :-pharmacology

Topic :- Antimicrobial Drugs

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Which the following drugs cannot used patient with Multi drug resistant Tuber

Subject :-pharmacology

Topic :- Antimicrobial Drugs

following drugs cannot used patient with Multi drug resistant Tuberculosis CiprofloxacinTobramycin ClarithromycinAmikacin aminoglycoside group drug used various bacterial infection particulary gram negative exterts its action inhibiting bacterial 30S and 50S ribosome preventing formation 70S complex not used antimycobacterial Other aminoglycosides such streptomycin and amikacin used antimycobacteriasl Ref: Richard Finkel Michelle Alexia Clark Pamela Champe Luigi Cubeddu (2009) Chapter “Antimycrobials” book “Pharmacology” 4th Edition Lippincott Williams and Wilkins Publications United States Pages 399-406 Tripathy 5th Edition Pages 684 699 .......

Which the following anti-tubercular drug contraindicated pregnancy? Ethamb

Subject :-pharmacology

Topic :- Antimicrobial Drugs

following anti-tubercular drug contraindicated pregnancy EthambutolIsoniazidRifampicinStreptomycin Streptomycin bactericidal antibiotic first class drugs called aminoglycosides discovered and was first antibiotic remedy for tuberculosis derived from actinobacterium Streptomyces griseus Streptomycin cannot given orally but must administered regular intramuscular injections adverse effect this medicine ototoxicity highly contraindicated pregnancy because ototoxicity fetus Ref: Richard Finkel Michelle Alexia Clark Pamela Champe Luigi Cubeddu (2009) Chapter “Antimycrobials” book “Pharmacology” 4th Edition Lippincott Williams and Wilkins Publications United States Page 404 Tripathi 5th Edition Page 681.......

Regarding sulpha group drugs all the below statements are true, except: Sulfonam

Subject :-pharmacology

Topic :- Antimicrobial Drugs

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Which the following drugs decreases hepatic glucose output and improves peripheral

Subject :-pharmacology

Topic :- Hormones & Related Drugs

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48-year-old man presents with complaint non-bloody diarrhea and right lower

Subject :-pharmacology

Topic :- Hormones & Related Drugs

48-year-old man presents with complaint non-bloody diarrhea and right lower quadrant pain with palpable mass and tenderness states that this "flare-up" one worst has ever experienced Radiographic examination reveals evidence ulceration stricture and fistula development colon and small bowel following drugs would MOST useful for treating this patient Diphenoxylate and atropineHydrocortisone suppositoriesHyoscyaminePrednisone The patient presenting with signs and symptoms suggestive Crohn's disease idiopathic inflammatory process that can affect any portion alimentary tract This condition often characterized intermittent bouts low-grade fever diarrhea malaise and weight loss well focal tenderness and palpable tender mass lower abdomen There radiographic evidence ulceration stricturing fistulas small intestine and colon Nonpharmacologic therapy can efficacious some cases but more severe cases may require corticosteroids such prednisone dramatically suppress clinical signs and symptoms Antidiarrheal agents (eg diphenoxylate with atropine loperamide) should used very cautiously these patients since there very high risk toxic megacolon Hydrocortisone suppositories indicated for treatment distal ulcerative colitis not Crohn's disease Hyoscyamine anticholinergic agent that may alleviate postprandial abdominal pain patient with irritable bowel syndrome administered 30-60 minutes before meal Mesalamine 5-aminosalicylic acid derivative indicated for treatment ulcerative colitis Although this agent may provide some benefit treatment Crohn's disease prednisone drug choice for treatment acute "flare-ups" seen patients with this disease .......

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