The
correct answer is C
This
patient presents with primary amenorrhea, short stature, failure of development
of secondary sexual characteristics, and somatic abnormalities suggestive of
Turner’s syndrome (gonadal agenesis). This condition is most often caused by an
XC genotype, which is readily diagnosed by standard karyotype analysis.
Patients with androgen resistance syndrome may also present with primary
amenorrhea and have male level testosterone values and an XY karyotype, but
they have adequate breast development, normal stature, and no somatic
abnormalities. Patients with hyperprolactinemia may present with primary or
secondary amenorrhea, and they have normal stature and no somatic
abnormalities. Patients with primary hypothyroidism may present with amenorrhea
or precocious puberty, with or without growth retardation but without somatic
abnormalities. Low serum estradiol is a nonspecific finding in all cases of
amenorrhea with reduced pituitary or ovarian function.