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Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock

pathology mcqs questions

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Kidney biopsy from a child with hemolytic uremic syndrome characterist...

Subject :-

pathology

Correct answer :- *** Hidden ***

Explanation :-

in the microcirculation, which are composed of dense aggregates of platelets surrounded by fibrin which is referred to as thrombotic microangiopathy. This Thrombotic microa

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2013-03-25 21:53:42
Kidney biopsy from child with hemolytic uremic syndrome characteristically most likely presents features of: Thrombotic microangiopathy Proliferative glomerulonephritisFocal segmental glomerulosclerosisMinimal change disease hemolytic uremic syndrome therewide spread formation hyaline thrombi inmicrocirculation composeddense aggregatesplatelets surrounded fibrinreferred thrombotic microangiopathy This Thrombotic microangiopathycharacterized thrombosis capillaries arterioles throughoutbody microangiopathic hemolytic anemia thrombocytopenia and renal failure Ref: Robbins Pathologic BasisDisease 6th Edition Page 636-7; Current Diagnosis and Treatment Pediatrics 2012 Chapter
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Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


year old woman was admitted with history weakness for two months examination she has enlarged cervical lymph nodes and spleen Her hemoglobin was g/dl platelet count 109/L and total leukocyte count 109/L included 80% mature lymphoid cells with coarse clumped chromatin Bone marrow revealed nodular lymphoid infiltrate peripheral blood lymphoid cells were positive for CD5 CD20 and CD23 and were negative for CD79B and FMC-7 The histopathological examination lymph node this patient will most likely exhibit effacement lymph node arachitecture by: pseudofollicular pattern with proliferation centersA monomorphic lymphoid proliferation with nodular patternA predominantly follicular patternA diffuse proliferation medium large lymphoid cells with high mitotic ratePatient question stem showing features chronic lymphocytic leukemia Histopathological examination case CLL shows diffuse effacement lymphocyte architecture small medium sized lymphocyes with clumped chromatin indistinct absent nucleoli and scanty cytoplasm Chronic lymphocytic leukemia (CLL) clonal malignancy lymphocytes manifested clinically immunosuppression bone marrow failure and organ infiltration with lymphocytes Ref: Current Medical Diagnosis and Treatment 2012 Chapter .......

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


subtype Hodgkin's disease histogentically distinct from all other subtypes Nodular sclerosisMixed cellularityLymphocyte depletedNodular Lymphocyte predominant Nodular lymphocytic predominat Hodgkins disease now recognized entity distinct from classical Hodgkin’s disease lymphocyte predominant Hodgkin’s disease Reed sterberg cells eosinoplils istocytes sparse and predominant cell mature lymphocyte result disease may mistaken for diffuse small b-cell non-Hodgkin lymphoma Approximately patients with have lymphocyte predominant (NLPHL) type most often involves cervical axillary lymph nodes can affect patients all ages males more often than females and symptoms such fever weight loss and night sweats (also known symptoms) infrequent These patients risk for developing diffuse large B-cell lymphoma T-cell/histiocyte-rich large B-cell lymphoma Ref:The Andersnn Manual Medical Oncology 2nd Edition Chapter .......

Which the following vascular changes not observed during acute inflammation? Vas

Which the following vascular changes not observed during acute inflammation? Vas

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


following vascular changes not observed during acute inflammation VasodilationStasis bloodIncreased vascular permeabilityDecreased hydrostatic pressure acute inflammation there increase hydrostatic pressure due increased blood from vasodilation also associated with reduced osmotic pressure because protein leakage secondary increased permeability Normal hydrostatic pressure 3mmHg arterial end 1mmHg venous end Normal colloid osmotic pressure 25mmHg acute inflammation hydrostatic pressure may increase 50mm while osmotic pressure may reduce 20mm Ref: Robbins Pathologic Basis Disease 6th Edition Pages 53-4 .......

Which the following statement not true? Patients with IgD myeloma may present wit

Which the following statement not true? Patients with IgD myeloma may present wit

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


following statement not true Patients with IgD myeloma may present with evident M-spike serum electrophoresisA diagnosis plasma cell leukemia can made circulating peripheral blood plasma blasts comprise 14% peripheral blood white cells smoldering myeloma plasma cells constitute 10-30% total bone marrow cellularityIn patient with multiple myeloma monoclonal light chain may detected both serum and urinePlasma cell leukemia diagnosed there more than 20% plasma cells peripheral blood and absolute plasma content least 2000 per microliter Ref: Manual Clinical Hematology Joseph Mazza 3rd Edition Page 259 .......

Which the following statements pertaining leukemia correct? Blasts acute

Which the following statements pertaining leukemia correct? Blasts acute

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


following statements pertaining leukemia correct Blasts acute myeloid leukemia typically Sudan black negativeBlasts acute lymphoblastic leukemia typically myeloperoxidase positiveLow leucocyte alkaline phosphatase score characteristically seen blastic phase chronic myeloid leukemiaTartarate resistant acid phosphatase positivity typically seen hairy cell leukemiaHairy cell leukemia uncommon chronic lymphoproliferative disorder characterized circulating lymphocytes that display prominent cytoplasmic projections hairy cells have characteristic histochemical staining pattern with tartrate-resistant acid phosphatase (TRAP) malignancy hematopoietic stem cells differentiated mature B-lymphocytes with hairy cytoplasmic projections Ref: Current Medical Diagnosis and Treatment 2012 Chapter .......

Which the following the classification proposed the International Lymphoma Study

Which the following the classification proposed the International Lymphoma Study

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


following classification proposed International Lymphoma Study Group for non-Hodgkin's lymphoma Kiel classificationREAL classification WHO classificationRappaport classificationThe classification proposed International Lymphoma Study Group for non-Hodgkin's lymphoma known REAL classification combining morphologic immunologic cytogenetic and molecular features this classification proposed biologically well defined lymphoma entities This classification placed emphasis underlying biologic aberration specific lymphoma subtypes has included much larger range lymphomas starting with precursor cells both and lines and also including lymphocytic cells different zones node like mantle zone and marginal zone Ref: Malignant Lymphomas Volume Michael Page 1;Textbook Pathology Datta 2nd Edition Page 878 .......

Which the following complications most likely occur after recieving several units

Which the following complications most likely occur after recieving several units

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


following complications most likely occur after recieving several units blood transfusion Metabolic alkalosis Metabolic acidosisRespiratory alkalosisRespiratory acidosis Banked blood has and acidotic After massive transfusion citrate stored blood converted into bicarbonate resulting metabolic alkalosis Ref: Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects Christopher Hillye Page 291 Yao and Artusio's Anesthesiology: Problem-Oriented Patient Management Fun-Sun Yao 6th Edition Page 1148 .......

All the following are the good prognostic features Hodgkin's disease except: Haem

All the following are the good prognostic features Hodgkin's disease except: Haem

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


All following good prognostic features Hodgkin's disease except: Haemoglobin gm/dlWBC count 15000/mm3Absolute lymphocyte count 600/ul Age yrsPrognostic factors important patient for selecting management and predicting outcome for individual patients Lymphocyte count 600/ul bad prognostic factor hodgkins lymphoma Bad prognostic factors hodgkins disease are: Male Stage disease Serum albumin 4g/dl Hemoglobin g/dl Age WBC 15*199/l Lymphocyte 109/l Ref: Cancer and Its Management Robert Souhami Page 395 100 Questions Answers About Lymphoma Peter Holman 2nd Edition Page DeVita Hellman and Rosenberg's Cancer: Principles Practice Oncology Volume 1By Vincent DeVita 8th Edition Page 2182 .......

All the following statements about Hairy cell leukaemia are true except: Splenomegal

All the following statements about Hairy cell leukaemia are true except: Splenomegal

Subject :-pathology

Topic :- Tissue Renewal, Repair, and Regeneration -- Hemodynamic Disorders, Thromboembolic Disease, and Shock


All following statements about Hairy cell leukaemia true except: Splenomegaly conspicuousResults from expansion neoplastic lymphocytes Cells positive for Tartarate Resistant Acid PhosphataseThe cells express CD25 consistently Hairy cell leukemia uncommon cell lymphoproliferative disorder constitute all forms leukemia Median age occurrence 55years Male female ratio 5:1 Most patients asymptomatic and diagnosed following incidental finding spleenomegaly cytopenia Some can present with fatigue weakness weight loss and occasionally fever and night sweats Ref: Oxford Desk Reference Oncology Thankamma Ajithkumar Page 486 .......

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